Efficacy of Local Delivery of Recombinant Tissue Plasminogen Activator for Vein Thromboembolic Syndrome
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چکیده
منابع مشابه
Efficacy of Local Delivery of Recombinant Tissue Plasminogen Activator for Vein Thromboembolic Syndrome
Tissue plasminogen activator (tPA) is a potent thrombolytic agent and as a consequence, bleeding is a major side effect associated with its use. We here describe a 72 year-old woman with a single kidney who was admitted to our hospital because of renal trauma associated with an accident. A large thrombus associated with the central venous line developed close to the wall of the inferior vena ca...
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Low molecular size additives such as L-arginine and the redox compounds have been used both in the culturemedium and in vitro refolding to increase recombinant proteins production. Additives increase proteinrefolding and yield of active proteins by suppressing aggregate formation or enhancing refolding process.In this work, a comparative study was performed on refolding of rec...
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Background: Thrombolytic therapy is the recommended treatment of acute ischemic stroke. It is crucial to evaluate the treatment results with recombinant Tissue Plasminogen Activator (r-TPA) in patients with acute stroke. Objectives: This study aimed to evaluate treatment outcomes with r-TPA in patients with acute stroke in a referral stroke center in Iran. Materials & Methods: In this retrosp...
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Background:Echogenic liposomes (ELIPs) encapsulate drugs and gas bubbles within lipid vesicles. The destruction of ELIPs in response to MHz and kHz ultrasound waves has been studied previously. Applying ultrasound above a certain threshold causes encapsulated gas bubbles destruct rapidly by fragmentation or more slowly by acoustically driven diffusion. This study compares the d...
متن کاملDifferences in clot preparation determine outcome of recombinant tissue plasminogen activator treatment in experimental thromboembolic stroke.
BACKGROUND AND PURPOSE Thrombin-induced clots used in experimental thromboembolic stroke differ from clots forming spontaneously under clinical conditions. We investigated whether this difference influences the efficacy and outcome of thrombolytic treatment. METHODS In rats, the middle cerebral artery was occluded by intracarotid injection of fibrin-rich clots, prepared either according to es...
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ژورنال
عنوان ژورنال: The Open Cardiovascular Imaging Journal
سال: 2011
ISSN: 1876-5386
DOI: 10.2174/1876538601103010004